anyone here tapered off Mirtazapine and have insomnia?

Johnb · 2026-05-16T17:06:46-07:00

Hey there I spent 2 years tapering off Mirtazapine going from 30mg to 0.4mg , making my own liquid formulation and mostly following a hyperbolic taper. I came off in November 2025. I hit extreme insomnia around weeks 6-10 ( early jan- mid Feb), stabilised somewhat and now having intermittent insomnia but still quite brutal at times, leading to zero or close to zero sleep. Depending who you talk to, most medical people will say the Mirtazapine withdrawal effect is negligible and im dealing with the original issue i have - anxiety and sleep issues. However, theres a trend towards realising that coming off meds, even if slowly, can take a very long time before stability. ( i.e theMaudsley report). A while ago it was suggested by a psychologist that i may have Cyclothymia or Bipolar II. so, now i am at the stage of investigating this properly and wondering how to navigate the murky water of what is what- im still suffering withdrawal and hence wait things out vs possibly needing new medication if properly diagnosed with the above. Please excuse my rambling and i hope i am clear here. Is there anyone able to relate, been in a similar position and offer any suggestions? Thanks in advance

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May 16, 2026 at 5:06 pm #99546
Johnb
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Hey there

I spent 2 years tapering off Mirtazapine going from 30mg to 0.4mg , making my own liquid formulation and mostly following a hyperbolic taper. I came off in November 2025.
I hit extreme insomnia around weeks 6-10 ( early jan- mid Feb), stabilised somewhat and now having intermittent insomnia but still quite brutal at times, leading to zero or close to zero sleep.

Depending who you talk to, most medical people will say the Mirtazapine withdrawal effect is negligible and im dealing with the original issue i have – anxiety and sleep issues.
However, theres a trend towards realising that coming off meds, even if slowly, can take a very long time before stability. ( i.e theMaudsley report).

A while ago it was suggested by a psychologist that i may have Cyclothymia or Bipolar II.
so, now i am at the stage of investigating this properly and wondering how to navigate the murky water of what is what- im still suffering withdrawal and hence wait things out vs possibly needing new medication if properly diagnosed with the above.

Please excuse my rambling and i hope i am clear here. Is there anyone able to relate, been in a similar position and offer any suggestions?

Thanks in advance
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